Vitamin D and K2 have numerous immunological properties that play a vital role in limiting the acquisition and severity of COVID-19. Vitamin D insufficiency has been associated with an increased risk of acquiring COVID-19 and from dying from the disease. Multivitamin contains Vitamin C which has important anti-inflammatory, antioxidant, and immune-enhancing properties, including increased synthesis of type I interferons which are an important part of the immune response. Probiotic contains Bifidobacterium and COVID-19. Low levels of Bifidobacterium may predispose to COVID-19 and increase its severity.